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Ultra Anti-Aging Cream active potent non-neutralized glycolic acid (AHA)

Ultra Anti-Aging Cream active potent non-neutralized glycolic acid (AHA)

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Dermatologist's Choice Ultra Anti-Aging Face Cream Retinoid Alternative Extra Strength Resurfacing Cream with Non-Neutralized Glycolic Acid- Professional-strength retinoid alternative treatment formulated with non-neutralized glycolic acid to address fine lines, wrinkles, dark spots and hyperpigmentation, enlarged pores, uneven texture and tone, and tired-looking skin.

This professional-grade anti-aging moisturizer works to correct the appearance of uneven texture and tone with non-neutralized glycolic acid for firmer, smoother, brighter, more youthful-looking skin.

15% Non-Neutralized Glycolic Acid: To provide maximum benefit, this cream contains the most active form of glycolic acid to help resurface and renew skin. You'll likely feel a tingling sensation after using this product because of its potency—and that's a good thing! Shea Butter & Vitamin E: Promote nourished skin while defending skin from free radical damage

Best active non-neutralized glycolic product in a luxurious moisturizing cream. Our most potent active, non-neutralized glycolic acid rivals the effectiveness of prescription competitors. If you're looking for a moisturizer that will actually brighten, smooth, and soften your skin, this is it. Key benefits of the Ultra Anti-Aging Cream include exfoliating, brightening, anti-aging, TK.

VOGUE ft. Ultra Anti-Aging Cream, "Best Glycolic Acid Products" Read the article.

VOGUE ft. Dr. B, "Tretinoin Skincare Routine" Read the article.

US Weekly ft. Ultra Anti-Aging Cream, "Enjoy the Fountain of Youth with These Skincare Picks" Read the article.

Compare our moisturizers. Learn More

*Feel the tingle, see the results. Some bumps/purging of the skin is normal after application. Clears in a couple days. This is the skin's natural exfoliation process.*

Dr. Bottiglione recommends for oily, normal, combination, mature, acne-prone, dry skin types.

Dermatologist's Choice formulas are created and developed by board-certified dermatologist Dr. Richard Bottiglione, who has over 50 years of experience in helping patients achieve their skin goals. Rather than rely on trendy ingredients, Dermatologist's Choice products feature actives that are clinically proven to transform skin. Each formula is cruelty-free, vegan, paraben-free, and designed to give you professional-grade results at home.

SIZE

50 mL / 1.7 oz tube

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Strongest over the counter active glycolic acid product

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Instantly brightens skin and helps firm wrinkles in weeks

HOW TO APPLY

At night, target major skin concerns (wrinkles around the eyes and mouth, dark spots, and pimples) by applying the Ultra Anti-Aging Cream to face and neck once a week for three weeks. Increase treatment by adding a day each week as skin tolerates. For best results, it's recommended to apply at least three days a week. Apply other Dermatologist's Choice moisturizers on top as needed.

Derm Tip: For those who have never used non-neutralized Glycolic Acid before, start with our mild Facial Enhancement Cream daily moisturize with non-neutralized Glycolic to build tolerance to the powerful treatment ingredient. If skin comfortably tolerates the Facial Enhancement Cream it is possible to take the next step by applying the Ultra Anti-Aging Cream.

Key Ingredients

Active non-neutralized Glycolic (AHA) - Naturally occurring from sugar cane, Glycolic molecules are the optimal size to penetrate the pores to deeply cleanse and break the bonds of dry, damaged skin. It promotes exfoliation for a fresh glow while stimulating collagen production.

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Shea Butter - helps protects against skin dryness and accelerates healing of superficial wounds and irritations

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Tocopheryl Acetate (Vitamin E Acetate) - the antioxidant helps defend skin from pollution and other environmental stressors that lead to signs of aging

See all ingredients

Exfoliates the surface layer of dead skin cells

Targets a wide range of skin concerns successfully

Smooths fine lines and wrinkles

Evens out hyperpigmentation 

Increase collagen production

Strengthens skin elasticity

Cream formulation reduces irritation

Apply a pea-sized amount to face and neck once a week in the evening for three weeks, increasing your application by one day each week as your skin adjusts to this potent treatment. Layer other moisturizers on top as needed.

Some bumps or purging of the skin is normal after application and is a sign that the treatment is effectively exfoliating your skin. As you continue to use the product, the purging will dissipate and clarity will improve.

Apply moisturizer if the tingle sensation is too much. In the morning, apply Facial Enhancement Cream and sunscreen.

If you are new to non-neutralized glycolic acid and have never used this product or our Glycolic Cleansing Peel Pads before, we recommend starting with our Facial Enhancement Cream to build tolerance.

Caution: For external use only.

Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Over 40 Years Utilizing Fully Active Ingredients

Formulated in 1981 by Dr. Bottiglione, we care for your skincare the way your dermatologist would by using potent medical-grade treatments that have outlasted all the trends in skincare. You’ll get refreshed, rejuvenated skin and feel healthier and more confident.

Learn more about our flagship ingredient, non-neutralized, glycolic acid

Dr. Bottiglione headshot

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In office treatment alternative for the improvement of exfoliating, brightening, anti-aging, keratosis pilaris (KP), often called "chicken skin".

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Less noticeable fine lines & wrinkles
Rough texture is visibly smoothed, fading the look of fine lines and wrinkles.

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More radiant-looking skin
Resurfaced, moisturized skin appears to glow from within and dark spots look diminished.

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Retinoid alternative
Provides results comparable to those of a prescription-strength retinoid with better tolerance.

Key Ingredients

Active non-neutralized Glycolic (AHA) - Naturally occurring from sugar cane, Glycolic molecules are the optimal size to penetrate the pores to deeply cleanse and break the bonds of dry, damaged skin. It promotes exfoliation for a fresh glow while stimulating collagen production.

Clears Pores Icon

Shea Butter - helps protects against skin dryness and accelerates healing of superficial wounds and irritations

Kill Acne Icon

Tocopheryl Acetate (Vitamin E Acetate) - the antioxidant helps defend skin from pollution and other environmental stressors that lead to signs of aging

See all ingredients

Exfoliates the surface layer of dead skin cells

Targets a wide range of skin concerns successfully

Smooths fine lines and wrinkles

Evens out hyperpigmentation 

Increase collagen production

Strengthens skin elasticity

Cream formulation reduces irritation

Apply a pea-sized amount to face and neck once a week in the evening for three weeks, increasing your application by one day each week as your skin adjusts to this potent treatment. Layer other moisturizers on top as needed.

Some bumps or purging of the skin is normal after application and is a sign that the treatment is effectively exfoliating your skin. As you continue to use the product, the purging will dissipate and clarity will improve.

Apply moisturizer if the tingle sensation is too much. In the morning, apply Facial Enhancement Cream and sunscreen.

If you are new to non-neutralized glycolic acid and have never used this product or our Glycolic Cleansing Peel Pads before, we recommend starting with our Facial Enhancement Cream to build tolerance.

Caution: For external use only.

Sunburn Alert: This product contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.

Over 40 Years Utilizing Fully Active Ingredients

Formulated in 1981 by Dr. Bottiglione, we care for your skincare the way your dermatologist would by using potent medical-grade treatments that have outlasted all the trends in skincare. You’ll get refreshed, rejuvenated skin and feel healthier and more confident.

Learn more about our flagship ingredient, non-neutralized, glycolic acid

Dr. Bottiglione headshot

The gold standard for effective age management.

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Complete your routine with one of our sets

Age Management Sets

Age with ease and less of the fine lines with these next-level medical grade skincare solutions.

Acne Solutions

Remove impurities from pores, reduce breakouts, and smooth the skin. Star seeing clearer skin in days.

Dry & Sensitive Skin

Replenish the skin's moisture, protect the skin's natural barrier, and soothe irritation on the skin with these time-tested products.

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All Ingredients

Water (Aqua), Glycolic Acid, Butyrospermum Parkii (Shea Butter) Unsaponifiables, Cetyl Alcohol, Ethylhexyl Stearate, C12-15 Alkyl Benzoate, Glyceryl Stearate, Stearyl Alcohol, PEG-100 Stearate, Magnesium Aluminum Silicate, Sodium Hydroxide, Propylene Glycol, Glycerin, Ceteth-20, Pentylene Glycol, Tocopheryl Acetate (Vitamin E Acetate), Sorbic Acid, Disodium EDTA, Phenoxyethanol, Benzyl Alcohol, Tetrasodium EDTA, Potassium Sorbate, Tocopherol

All Ingredients

Water (Aqua), Glycolic Acid, Butyrospermum Parkii (Shea Butter) Unsaponifiables, Cetyl Alcohol, Ethylhexyl Stearate, C12-15 Alkyl Benzoate, Glyceryl Stearate, Stearyl Alcohol, PEG-100 Stearate, Magnesium Aluminum Silicate, Sodium Hydroxide, Propylene Glycol, Glycerin, Ceteth-20, Pentylene Glycol, Tocopheryl Acetate (Vitamin E Acetate), Sorbic Acid, Disodium EDTA, Phenoxyethanol, Benzyl Alcohol, Tetrasodium EDTA, Potassium Sorbate, Tocopherol